Company Profile

Lyell Immunopharma Stock Price, News & Analysis

Ticker:
LYEL
Exchange:
NASDAQ
Sector:
Biopharma
Location:
United States

Stock performance

14.21 USD (+5.65%)

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Last updated: August 6, 2026

347M USD

Market cap

Why the stock is moving

The latest monitored company update is “Lyell Immunopharma Reports Business Highlights and Financial Results for the Second Quarter 2026.” The corresponding closing-price reaction is not yet available.

Company overview

Next-Generation CAR-T Therapies

Lyell Immunopharma develops engineered CAR-T cell therapies intended to improve response depth, durability and activity in hematologic and solid tumors.

Ronde-cel

Ronde-cel is an autologous CAR-T product with an OR-gated design targeting either CD19 or CD20. Its manufacturing process enriches less-differentiated T cells to support persistence in large B-cell lymphoma.

Pivotal LBCL Programs

PiNACLE is a pivotal single-arm study in third- or later-line large B-cell lymphoma. PiNACLE-H2H is a randomized Phase 3 trial comparing ronde-cel directly with established CD19 CAR-T therapies in second-line disease.

LYL273

LYL273 is a separate engineered cell therapy in Phase 1 development for metastatic colorectal cancer, extending Lyell's platform into solid tumors.

Future catalysts

Additional PiNACLE data in the second half of 2026.

LYL273 safety update in the first half of 2026 and clinical-outcomes update in the second half of 2026.

Pivotal PiNACLE data around mid-2027, followed by a planned BLA submission in 2027.

Recent news

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Frequently Asked Questions

What is the current stock price of Lyell Immunopharma (LYEL)?

Lyell Immunopharma (LYEL) most recently closed at 14.21 USD, a +5.65% move versus the previous session.

What is the market cap of Lyell Immunopharma (LYEL)?

Lyell Immunopharma currently has a market capitalization of 347M USD on BioPharmSignal.

What does Lyell Immunopharma do?

Next-Generation CAR-T Therapies Lyell Immunopharma develops engineered CAR-T cell therapies intended to improve response depth, durability and activity in hematologic and solid tumors. Ronde-cel Ronde-cel is an autologous CAR-T product with an OR-gated design targeting either CD19 or CD20. Its manufacturing process enriches less-differentiated T cells to...

On which exchange is LYEL stock listed?

Lyell Immunopharma (LYEL) is associated with NASDAQ, United States, Biopharma.

What is CAR-T?

Next-Generation CAR-T Therapies Lyell Immunopharma develops engineered CAR-T cell therapies intended to improve response depth, durability and activity in hematologic and solid tumors.

Which conditions is Lyell Immunopharma targeting with CAR-T?

Lyell Immunopharma is associated with cancer therapeutics based on its company overview and current catalyst commentary.

How does Lyell Immunopharma describe recent progress with CAR-T?

Additional PiNACLE data in the second half of 2026. LYL273 safety update in the first half of 2026 and clinical-outcomes update in the second half of 2026. Pivotal PiNACLE data around mid-2027, followed by a planned BLA submission in 2027.

What is Next-Generation?

Next-Generation CAR-T Therapies Lyell Immunopharma develops engineered CAR-T cell therapies intended to improve response depth, durability and activity in hematologic and solid tumors.